Chem Eng (Hungary) Medicinal Chemistry, PhD (Budapest) Medicinal Chemistry, DSc (Hungarian Academy of Science) Drug Delivery.
Position: 
ARC Australian Professorial Fellow, Chair in Biological Chemistry, Professor of Pharmacy, Group Leader IMB Division of Structural Biology
Room: 
1121
Phone: 
+61 7 3346 9892
Biography: 

Professor Toth was a Postdoctoral Fellow at Carleton University, Ottawa Canada (1974-76, Prof J.W. ApSimon). He returned to Hungary to work as a Research Associate (1977-82), then Scientific Group Leader (1982-1987) at the Central Research Institute for Chemistry, Hungarian Academy of Science. Professor Toth joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 before relocating to The University of Queensland in 1998. Professor Toth has since been appointed as a Fellow of both the Royal Australian Chemical Institute (2008) and the Queensland Academy of Arts and Sciences (2009). He has more than 300 publications and 43 patents.

Brief Research Description: 
Novel drug delivery systems
Research Focus and Collaborations: 

Professor Toth’s major research interests are drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides and nucleotides. New developments in drug/vaccine delivery will clearly have a strong economic impact on the pharmaceutical and biotechnology industries. At the School of Pharmacy, University of London, and at The University of Queensland, Professor Toth has built up a strong, very productive research group (presently about 25 members), where the research orientation is well suited to the direction of modern multidisciplinary pharmaceutical sciences. Professor Toth also has a keen interest in research commercialisation. He is one of the founding members of Alchemia (listed on the Australian Stock Exchange), Implicit Biosciences Pty Ltd and Neurotide. Professor Toth is also a key partner in the Queensland Preclinical Drug Development Facility (TetraQ), established in 2005 as a world-class facility to provide integrated preclinical drug development services to Queensland and Australian biotechnology companies engaged in human therapeutics development. Professor Toth’s primary research goal is to develop versatile delivery mechanisms that can be adapted to suit a broad range of drug and vaccine candidates.

Funded Projects: 

NHMRC Program Grant 2013-2017
Tropical Disease – Immunity, pathogenesis and vaccine development: global translation.
Total value of grant: $17, 100, 585

ARC Discovery Grant 2011-2015
Liposaccharide based peptide and vaccine delivery systems: improving the bioavailability and immunogenicity of LHRH.
Total value of grant: $1, 030, 000

NHMRC Program Grant 2004-2012
Tropical Infectious Diseases – Pathogenesis and vaccine research.
Total value of grant: $22, 000, 000

ARC Discovery Project Grant 2010-2012
Lipid and carbohydrate based systems to target and deliver peptide drug candidates to specific cells.
Total value of grant: $750, 000

Teaching: 

Chemistry, medicinal chemistry and drug delivery.

Significant Professional Activities and Awards: 
  • Editor in Chief: Current Drug Delivery

  • Editor in Chief: Drug Delivery letters

  • Associate Editor: Medicinal Chemistry

  • Board Member: Mini Reviews in Medicinal Chemistry, Drug Design and Reviews Online

  • Scientific Advisory Board Member: Implicit Bioscience Pty Ltd.

  • Member ARC College of Experts 2008-2010

  • Business/Higher Education Round Table (BHERT) Award: Outstanding Achievement in International Collaborative R&D 2005

  • Adrian Albert Award RACI Biomolecular Chemistry Division

Group Members:

Dr Waleed Hussein Postdoctoral Research Fellow

Dr Rachel Stephenson Postdoctoral Research Fellow

Selected Publications: 
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