Chem Eng (Hungary) Medicinal Chemistry, PhD (Budapest) Medicinal Chemistry, DSc (Hungarian Academy of Science) Drug Delivery.
Position: 
ARC Australian Professorial Fellow, Chair in Biological Chemistry, Professor of Pharmacy, Group Leader IMB Division of Structural Biology
Room: 
1121
Phone: 
+61 7 3346 9892
Biography: 

Professor Toth was a Postdoctoral Fellow at Carleton University, Ottawa Canada (1974-76, Prof J.W. ApSimon). He returned to Hungary to work as a Research Associate (1977-82), then Scientific Group Leader (1982-1987) at the Central Research Institute for Chemistry, Hungarian Academy of Science. Professor Toth joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 before relocating to The University of Queensland in 1998. Professor Toth has since been appointed as a Fellow of both the Royal Australian Chemical Institute (2008) and the Queensland Academy of Arts and Sciences (2009). He is an elected Member (external) of the Hungarian Academy of Sciences (2016). He has more than 360 publications and 45 patents.

Brief Research Description: 
Novel drug delivery systems
Research Focus and Collaborations: 

Professor Toth’s major research interests are drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides and nucleotides. New developments in drug/vaccine delivery will clearly have a strong economic impact on the pharmaceutical and biotechnology industries. At the School of Pharmacy, University of London, and at The University of Queensland, Professor Toth has built up a strong, very productive research group (presently about 25 members), where the research orientation is well suited to the direction of modern multidisciplinary pharmaceutical sciences. Professor Toth also has a keen interest in research commercialisation. He is one of the founding members of Alchemia (listed on the Australian Stock Exchange), Implicit Biosciences Pty Ltd and Neurotide. Professor Toth is also a key partner in the Queensland Preclinical Drug Development Facility (TetraQ), established in 2005 as a world-class facility to provide integrated preclinical drug development services to Queensland and Australian biotechnology companies engaged in human therapeutics development. Professor Toth’s primary research goal is to develop versatile delivery mechanisms that can be adapted to suit a broad range of drug and vaccine candidates.

Funded Projects: 

NHMRC PROGRAM GRANT 201802022

Tropical diseases: Translating Discoveriies Into Better health

Total value of the grant: $19,800,000

 

NHMRC Project Grant 2017-2019

Understanding the myometrial transition at term and preterm labour to guide tocolysis

Total value of the grant:$808,447

 

NHMRC Program Grant 2013-2017
Tropical Disease – Immunity, pathogenesis and vaccine development: global translation.
Total value of grant: $17, 100, 585

ARC Discovery Grant 2011-2015
Liposaccharide based peptide and vaccine delivery systems: improving the bioavailability and immunogenicity of LHRH.
Total value of grant: $1, 030, 000

NHMRC Program Grant 2004-2012
Tropical Infectious Diseases – Pathogenesis and vaccine research.
Total value of grant: $22, 000, 000

ARC Discovery Project Grant 2010-2012
Lipid and carbohydrate based systems to target and deliver peptide drug candidates to specific cells.
Total value of grant: $750, 000

Teaching: 

Chemistry, medicinal chemistry and drug delivery.

Significant Professional Activities and Awards: 
  • Associate Editor: Medicinal Chemistry

  • Board Member: Mini Reviews in Medicinal Chemistry, Drug Design and Reviews Online

  • Scientific Advisory Board Member: Implicit Bioscience Pty Ltd.

  • Member ARC College of Experts 2008-2010

  • Business/Higher Education Round Table (BHERT) Award: Outstanding Achievement in International Collaborative R&D 2005

  • Adrian Albert Award RACI Biomolecular Chemistry Division

Group Members:

Dr Mariusz Swarczynsky Post doctoral Research Fellow

Dr Waleed Hussein Postdoctoral Research Fellow

Dr Rachel Stephenson Postdoctoral Research Fellow

PhD students

Student’s Name

 
 

 

Enrol-ment

Submit-ted

Awarded

Supervisors

PhD, ongoing

Ummey Jannatun Nahar

10/18

 

 

 

PhD, ongoing

Ahmed Shalash

10/18

 

 

Toth, Skwarczynski

PhD, ongoing

Shakeel Khan

10/18

 

 

Toth, Skwarczynski

PhD, ongoing

Tanjir Islam

2/18

 

 

Toth, Skwarczynski

PhD, ongoing

Viet Tam Duong

7/18

 

 

Toth, Skwarczynski

PhD, ongoing

Nedaa Alhabri

1/18

 

 

Toth, Skwarczynski

PhD, ongoing

Armira Azuar

4/18

 

 

Toth, Skwarczynski

PhD, ongoing

Jieru Yang

8/18

 

 

Toth, Skwarczynski

PhD, ongoing

Mohammad Faruck

2/18

 

 

Toth, Skwarczynski

PhD, ongoing

Chuankai Dai

01/17

 

 

Toth, Stephenson

PhD, ongoing

Lili Zhao

10/16

 

 

Toth, Skwarczynski

PhD, ongoing

Stacey Bartlett

10/15

 

 

Toth, Skwarczynski

PhD, ongoing

Reshma Nevagi

08/15

 

 

Toth, Skwarczynski

PhD, submitted

Wei Dai

08/14

2018

 

Toth, Moyle

PhD, submitted

Farjana Khatun

04/14

2018

 

Toth, Stephenson

PhD, completed

Noushin Jaberolansar

04/14

2018

2018

Toth, Paul Young

PhD, completed

Anjuman Ara Begum

04/14

2018

2018

Toth, Skwarczynski

PhD, completed

Khairul Kamaruzaman

11/13

2017

2017

Toth, Moyle

PhD, completed

Yu Wan

10/13

2017

2017

Toth, Moyle

PhD, completed

Guangzu Zhao

02/15

2018

2018

Toth, Skwarczynski

PhD, completed

Nirmal Marasini

07/13

11/16

2017

Toth, Skwarczynski

PhD, completed

Sharareh Eskandari

10/12

01/16

2016

Toth, Stephenson

PhD, completed

Bita Sedaghat

10/12

04/16

2016

Toth, Stephenson

PhD, completed

Fazren Azmi

10/12

05/16

2016

Toth, Skwarczynski

PhD, completed

Khairunnisa (Nisa) Abdulghaffar

10/12

04/16

2016

Toth, Skwarczynski

PhD, completed

Saranya Chandrudu

10/12

04/16

2016

Toth, Skwarczynski

PhD, completed

Shayli Varasteh Moradi

10/12

05/15

2016

Toth, Varamini

PhD, completed

Ashwin Kumar Giddam

01/12

07/15

03/16

Toth, Zaman

PhD, completed

Cheng-Hung (Hugo) Chang

02/11

08/15

 

Toth, Varamini

PhD, completed

Abdullah Ahmad Fuaad

07/11

02/15

 

Toth, Skwarczynski

PhD, completed

Tzu-Yu (Vicky) Liu

04/11

10/14

02/15

Skwarczynsk, Toth

PhD, completed

Daryn Goodwin

03/10

11/13

 

Toth, Simerska

PhD, completed

Pegah Varamini

02/09

08/12

12/12

Toth, Smith

PhD, completed

Mehfuz Zaman

08/08

09/11

03/12

 

PhD, completed

Ian Chun Lin

02/08

-

 

 

PhD

Yanquin Lu

Wthdr

 

 

Minchin (80%), Toth (20%)

PhD, completed

Adel Abdel-Rahim

2006

12/09

 

Toth

PhD

Abdur Rashid

Wthdr

 

 

 

PhD, completed

Abu-Baker M Abdel-Aal

08/06

08/09

11/09

Toth (70%), Good (30%)

PhD, completed

Makan Khoshnejad

05/06

 

 

Toth, Young, Minchin

PhD, completed

Wei Zhong

03/06

02/10

 

Toth, Alewood

PhD, completed

Daniel Coles

2006

04/10

 

Toth, Minchin

PhD, completed

Karen Phillipps

12/05

 

 

Toth (50%), Wykes (30%), Brown (20%)

PhD, completed

Cecile Cros

08/05

12/08

01/10

Toth (50%), Blanchfield (50%)

PhD, completed

Shu (Yvonne) Yang

 

 

 

Minchin (80%), Toth (20%)

PhD, completed

Christopher Peatey

 

 

 

QIMR, Toth

PhD, completed

Gysell Broadhurst

 

 

 

Minchin, Toth

PhD, completed

Ming-Tao (Roger) Liang

03/05

 

 

Toth (40%), Monteiro (20%), Blanchfield (25%)

PhD, completed

Andrew Bulmer

02/02

 

 

Coombes (50%), Toth (25%), Blanchfield (25%)

PhD, completed

Yasuko Koda

08/03

 

 

Blanchfield (50%), Toth (50%)

PhD, completed

Peter Moyle

03/03

07/06

 

Toth, Blanchfield, Olive

PhD, completed

Sasha Ozarko

Wthdr

 

 

 

PhD, completed

Enoch Chan

02/00

10/04

04/05

Toth (80%), Bruce (20%)

PhD, completed

Ben Ross

02/99

06/04

11/04

Toth (80%), Blanchfield (10%), Mc Geary (10%)

 

 

Selected Publications: